TLR4 anticorps

N° du produit ABIN7249750

L’anticorps Souris Monoclonal anti-TLR4 a été validé pour IHC. Il convient pour détecter TLR4 dans des échantillons de Souris et Rat.

Aperçu rapide pour TLR4 anticorps (ABIN7249750)

Antigène: TLR4 (Toll-Like Receptor 4 (TLR4))

Reactivité: Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TLR4 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: 2E12C8

Détail du produit anti-TLR4 anticorps

Attributs du produit: Monoclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant protein corresponding to Mouse TLR4

Isotype: IgG

Information d'application

Indications d'application: IHC 1:200-1:800

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.8 mg/mL

Buffer: PBS with 0.02 % sodium azide, 1 % BSA and 50 % glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur TLR4

Antigène: TLR4 (Toll-Like Receptor 4 (TLR4))

Autre désignation: CD284

Sujet: TLR4,also named as CD284,belongs to the Toll-like receptor family. TLR4 cooperates with LY96 and CD14 to mediates the innate immune response to bacterial lipopolysaccharide (LPS). TLR4 acts via MYD88,TIRAP and TRAF6,leading to NF-kappa-B activation,cytokine secretion and the inflammatory response. Three alternatively spliced transcript variants that encode different protein isoforms have been described.

UniProt: Q9QUK6, Q9QX05

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteins